Advanced Bioconductor

In this course, we begin with approaches to visualization of genome-scale data, and provide tools to build interactive graphical interfaces to speed discovery and interpretation. 

We study out-of-memory approaches to the analysis of very large data resources, using relational databases or HDF5 as "back ends" with familiar R interfaces. Multiomic data integration is illustrated using a curated version of The Cancer Genome Atlas. 

Finally, we explore cloud-resident resources developed for the Encyclopedia of DNA Elements (the ENCODE project). These address transcription factor binding, ATAC-seq, and RNA-seq with CRISPR interference.

These courses make up two Professional Certificates and are self-paced: